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eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning
48S initiation complex (48S IC) formation is the first stage in the eukaryotic translation process. According to the canonical mechanism, 40S ribosomal subunit binds to the 5′-end of messenger RNA (mRNA) and scans its 5′-untranslated region (5′-UTR) to the initiation codon where it forms the 48S IC....
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231746/ https://ncbi.nlm.nih.gov/pubmed/25260592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku877 |
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