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eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning

48S initiation complex (48S IC) formation is the first stage in the eukaryotic translation process. According to the canonical mechanism, 40S ribosomal subunit binds to the 5′-end of messenger RNA (mRNA) and scans its 5′-untranslated region (5′-UTR) to the initiation codon where it forms the 48S IC....

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Pisareva, Vera P., Pisarev, Andrey V.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231746/
https://ncbi.nlm.nih.gov/pubmed/25260592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku877
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