Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP

The 40S subunit in 48S complexes formed at the initiation codon of mRNA is bound to eukaryotic initiation factor (eIF) 3, eIF1, eIF1A, and an eIF2/GTP/Met- [Formula: see text] ternary complex and can therefore not join a 60S subunit directly to form an 80S ribosome. We report that eIF5-induced hydro...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Unbehaun, Anett, Borukhov, Sergei I., Hellen, Christopher U.T., Pestova, Tatyana V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2004
Assuntos:	Research Papers
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15601822/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1255704
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