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Identification of 12Cysβ on tubulin as the binding site of tubulyzine

We have undertaken quantitative binding site studies in order to identify the binding site of the known microtubule destabilizing agents, the tubulyzines, in the tubulin dimer. Two different approaches were employed that utilized the tubulyzines and their derivatives. The first approach was based on...

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Bibliografiske detaljer
Main Authors: Kim, Yeoun Jin, Sackett, Dan L., Schapira, Matthieu, Walsh, Daniel P., Min, Jaeki, Pannell, Lewis K., Chang, Young-Tae
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1408322/
https://ncbi.nlm.nih.gov/pubmed/16266809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2005.09.069
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