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Identification of 12Cysβ on tubulin as the binding site of tubulyzine
We have undertaken quantitative binding site studies in order to identify the binding site of the known microtubule destabilizing agents, the tubulyzines, in the tubulin dimer. Two different approaches were employed that utilized the tubulyzines and their derivatives. The first approach was based on...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1408322/ https://ncbi.nlm.nih.gov/pubmed/16266809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2005.09.069 |
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