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Human Immunodeficiency Virus Type 1 Nucleocapsid Zn(2+) Fingers Are Required for Efficient Reverse Transcription, Initial Integration Processes, and Protection of Newly Synthesized Viral DNA
Human immunodeficiency virus type 1 (HIV-1) containing mutations in the nucleocapsid (NC) Zn(2+) finger domains have greatly reduced infectivity, even though genome packaging is largely unaffected in certain cases. To examine replication defects, viral DNA (vDNA) was isolated from cells infected wit...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140799/ https://ncbi.nlm.nih.gov/pubmed/12502862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1469-1480.2003 |
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