Characterization of the Block in Replication of Nucleocapsid Protein Zinc Finger Mutants from Moloney Murine Leukemia Virus

Mutagenesis studies have shown that retroviral nucleocapsid (NC) protein Zn(2+) fingers (-Cys-X(2)-Cys-X(4)-His-X(4)-Cys- [CCHC]) perform multiple functions in the virus life cycle. Moloney murine leukemia virus mutants His 34→Cys (CCCC) and Cys 39→His (CCHH) were able to package their genomes norma...

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Main Authors: Gorelick, Robert J., Fu, William, Gagliardi, Tracy D., Bosche, William J., Rein, Alan, Henderson, Louis E., Arthur, Larry O.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
主題:
Replication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC112836/
https://ncbi.nlm.nih.gov/pubmed/10482569
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