Characterization of the Block in Replication of Nucleocapsid Protein Zinc Finger Mutants from Moloney Murine Leukemia Virus

Mutagenesis studies have shown that retroviral nucleocapsid (NC) protein Zn(2+) fingers (-Cys-X(2)-Cys-X(4)-His-X(4)-Cys- [CCHC]) perform multiple functions in the virus life cycle. Moloney murine leukemia virus mutants His 34→Cys (CCCC) and Cys 39→His (CCHH) were able to package their genomes norma...

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Publié dans:	J Virol
Auteurs principaux:	Gorelick, Robert J., Fu, William, Gagliardi, Tracy D., Bosche, William J., Rein, Alan, Henderson, Louis E., Arthur, Larry O.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Replication
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8185-8195.1999
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