Human Immunodeficiency Virus Type 1 Nucleocapsid Zn(2+) Fingers Are Required for Efficient Reverse Transcription, Initial Integration Processes, and Protection of Newly Synthesized Viral DNA

Human immunodeficiency virus type 1 (HIV-1) containing mutations in the nucleocapsid (NC) Zn(2+) finger domains have greatly reduced infectivity, even though genome packaging is largely unaffected in certain cases. To examine replication defects, viral DNA (vDNA) was isolated from cells infected wit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Buckman, James S., Bosche, William J., Gorelick, Robert J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2003
Pynciau:
Replication
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC140799/
https://ncbi.nlm.nih.gov/pubmed/12502862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.2.1469-1480.2003
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