Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System

Targeted disruption of the retinoblastoma gene in mice leads to embryonic lethality in midgestation accompanied by defective erythropoiesis. Rb(−/−) embryos also exhibit inappropriate cell cycle activity and apoptosis in the central nervous system (CNS), peripheral nervous system (PNS), and ocular l...

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書誌詳細

出版年:	Mol Cell Biol
主要な著者:	MacPherson, D., Sage, J., Crowley, D., Trumpp, A., Bronson, R. T., Jacks, T.
フォーマット:	Artigo
言語:	Inglês
出版事項:	Taylor & Francis 2003
主題:	Cell Growth and Development
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12529408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.3.1044-1053.2003
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