Rb and N-ras Function Together To Control Differentiation in the Mouse

The product of the retinoblastoma tumor suppressor gene (Rb) can control cell proliferation and promote dif-ferentiation. Murine embryos nullizygous for Rb die midgestation with defects in cell cycle regulation, control of apoptosis, and terminal differentiation of several tissues, including skeleta...

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Bibliographic Details
Main Authors: Takahashi, Chiaki, Bronson, Roderick T., Socolovsky, Merav, Contreras, Bernardo, Lee, Kwang Youl, Jacks, Tyler, Noda, Makoto, Kucherlapati, Raju, Ewen, Mark E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC165732/
https://ncbi.nlm.nih.gov/pubmed/12861012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.15.5256-5268.2003
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