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Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System
Targeted disruption of the retinoblastoma gene in mice leads to embryonic lethality in midgestation accompanied by defective erythropoiesis. Rb(−/−) embryos also exhibit inappropriate cell cycle activity and apoptosis in the central nervous system (CNS), peripheral nervous system (PNS), and ocular l...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology
2003
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140709/ https://ncbi.nlm.nih.gov/pubmed/12529408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.3.1044-1053.2003 |
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