Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System

Targeted disruption of the retinoblastoma gene in mice leads to embryonic lethality in midgestation accompanied by defective erythropoiesis. Rb(−/−) embryos also exhibit inappropriate cell cycle activity and apoptosis in the central nervous system (CNS), peripheral nervous system (PNS), and ocular l...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	MacPherson, D., Sage, J., Crowley, D., Trumpp, A., Bronson, R. T., Jacks, T.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2003
Matèries:	Cell Growth and Development
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140709/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12529408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.3.1044-1053.2003
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