Disulfide-Linked Integrase Oligomers Involving C280 Residues Are Formed In Vitro and In Vivo but Are Not Essential for Human Immunodeficiency Virus Replication

The human immunodeficiency virus type 1 integrase (IN) forms an oligomer that integrates both ends of the viral DNA. The nature of the active oligomer is unclear. Recombinant IN obtained under reducing conditions is always in the form of noncovalent oligomers. However, disulfide-linked oligomers of...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Bischerour, Julien, Leh, Hervé, Deprez, Eric, Brochon, Jean-Claude, Mouscadet, Jean-François
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2003
נושאים:
Replication
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC140589/
https://ncbi.nlm.nih.gov/pubmed/12477818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.135-141.2003
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