Styrylquinolines, Integrase Inhibitors Acting Prior to Integration: a New Mechanism of Action for Anti-Integrase Agents

We have previously shown that styrylquinolines (SQLs) are integrase inhibitors in vitro. They compete with the long terminal repeat substrate for integrase. Here, we describe the cellular mode of action of these molecules. We show that SQLs do not interfere with virus entry. In fact, concentrations...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bonnenfant, Sabine, Thomas, Claire Marie, Vita, Claudio, Subra, Frédéric, Deprez, Eric, Zouhiri, Fatima, Desmaële, Didier, d'Angelo, Jean, Mouscadet, Jean François, Leh, Hervé
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Vaccines and Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC415813/
https://ncbi.nlm.nih.gov/pubmed/15140970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.11.5728-5736.2004
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