Styrylquinolines, Integrase Inhibitors Acting Prior to Integration: a New Mechanism of Action for Anti-Integrase Agents

We have previously shown that styrylquinolines (SQLs) are integrase inhibitors in vitro. They compete with the long terminal repeat substrate for integrase. Here, we describe the cellular mode of action of these molecules. We show that SQLs do not interfere with virus entry. In fact, concentrations...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Virol
मुख्य लेखकों: Bonnenfant, Sabine, Thomas, Claire Marie, Vita, Claudio, Subra, Frédéric, Deprez, Eric, Zouhiri, Fatima, Desmaële, Didier, d'Angelo, Jean, Mouscadet, Jean François, Leh, Hervé
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2004
विषय:
Vaccines and Antiviral Agents
ऑनलाइन पहुंच:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415813/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15140970/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.11.5728-5736.2004
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