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Disulfide-Linked Integrase Oligomers Involving C280 Residues Are Formed In Vitro and In Vivo but Are Not Essential for Human Immunodeficiency Virus Replication

The human immunodeficiency virus type 1 integrase (IN) forms an oligomer that integrates both ends of the viral DNA. The nature of the active oligomer is unclear. Recombinant IN obtained under reducing conditions is always in the form of noncovalent oligomers. However, disulfide-linked oligomers of...

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Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Bischerour, Julien, Leh, Hervé, Deprez, Eric, Brochon, Jean-Claude, Mouscadet, Jean-François
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140589/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.135-141.2003
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