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Inhibition of GLI1 gene activation by Patched1
Patched1 (PTCH1) is a human tumour suppressor that acts as an HH (Hedgehog) receptor protein and is important for embryonic patterning. PTCH1 mediates its effects through SMO (Smoothened) and represses the expression of HH target genes such as the transcription factor GLI1 (glioma 1) as well as PTCH...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1385998/ https://ncbi.nlm.nih.gov/pubmed/16229683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050941 |
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