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Inhibition of GLI1 gene activation by Patched1

Patched1 (PTCH1) is a human tumour suppressor that acts as an HH (Hedgehog) receptor protein and is important for embryonic patterning. PTCH1 mediates its effects through SMO (Smoothened) and represses the expression of HH target genes such as the transcription factor GLI1 (glioma 1) as well as PTCH...

詳細記述

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書誌詳細
主要な著者: Rahnama, Fahimeh, Shimokawa, Takashi, Lauth, Matthias, Finta, Csaba, Kogerman, Priit, Teglund, Stephan, Toftgård, Rune, Zaphiropoulos, Peter G.
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1385998/
https://ncbi.nlm.nih.gov/pubmed/16229683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050941
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