Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control

Autor Singh, Rajeev, Lauth, Matthias
Vydáno v J Dev Biol (2017)

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

Autor Singh, Rajeev, Dhanyamraju, Pavan Kumar, Lauth, Matthias
Vydáno v Oncotarget (2016)

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

Autor Lauth, Matthias, Spreafico, Fabio, Dethleffsen, Kathrin, Meyer, Michael
Vydáno 2002

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

Autor Lauth, Matthias, Bergström, Åsa, Shimokawa, Takashi, Toftgård, Rune
Vydáno 2007

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1

Autor Palaniswamy, Ramesh, Teglund, Stephan, Lauth, Matthias, Zaphiropoulos, Peter G, Shimokawa, Takashi
Vydáno 2010

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

Autor Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Vydáno 2016

Novel Human Glioma-associated Oncogene 1 (GLI1) Splice Variants Reveal Distinct Mechanisms in the Terminal Transduction of the Hedgehog Signal

Autor Shimokawa, Takashi, Tostar, Ulrica, Lauth, Matthias, Palaniswamy, Ramesh, Kasper, Maria, Toftgård, Rune, Zaphiropoulos, Peter G.
Vydáno 2008

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity

Autor Barski, Jaroslaw J., Denker, Brad M., Guan, Jiazhen, Lauth, Matthias, Spreafico, Fabio, Fertala, Andrzej, Meyer, Michael
Vydáno 2013

Inhibition of GLI1 gene activation by Patched1

Autor Rahnama, Fahimeh, Shimokawa, Takashi, Lauth, Matthias, Finta, Csaba, Kogerman, Priit, Teglund, Stephan, Toftgård, Rune, Zaphiropoulos, Peter G.
Vydáno 2006

Chronic Pancreatitis and Systemic Inflammatory Response Syndrome Prevent Impact of Chemotherapy with Gemcitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer()()

Autor Knoop, Richard F., Sparn, Moritz, Waldmann, Jens, Plassmeier, Lars, Bartsch, Detlef K., Lauth, Matthias, Hudemann, Christoph, Fendrich, Volker
Vydáno 2014

Ectopic Overexpression of Sonic Hedgehog (Shh) Induces Stromal Expansion and Metaplasia in the Adult Murine Pancreas

Autor Fendrich, Volker, Oh, Edwin, Bang, Seungmin, Karikari, Collins, Ottenhof, Niki, Bisht, Savita, Lauth, Matthias, Brossart, Peter, Katsanis, Nicholas, Maitra, Anirban, Feldmann, Georg
Vydáno 2011

Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

Autor Koeniger, Anke, Brichkina, Anna, Nee, Iris, Dempwolff, Lukas, Hupfer, Anna, Galperin, Ilya, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Adhikary, Till, Diederich, Wibke, Lauth, Matthias
Vydáno v Cancers (Basel) (2021)

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

Autor Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Vydáno v Nat Commun (2015)

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

Autor Schneider, Philipp, Bayo-Fina, Juan Miguel, Singh, Rajeev, Dhanyamraju, Pavan Kumar, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Vydáno v Nat Commun (2015)

The Immune Microenvironment in Pancreatic Cancer

Autor Huber, Magdalena, Brehm, Corinna U., Gress, Thomas M., Buchholz, Malte, Alashkar Alhamwe, Bilal, Pogge von Strandmann, Elke, Slater, Emily P., Bartsch, Jörg W., Bauer, Christian, Lauth, Matthias
Vydáno v Int J Mol Sci (2020)

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

Autor Joost, Simon, Almada, Luciana L., Rohnalter, Verena, Holz, Philipp S., Vrabel, Anne M., Fernandez-Barrena, Maite G., McWilliams, Robert R., Krause, Michael, Fernandez-Zapico, Martin E., Lauth, Matthias
Vydáno 2011

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Autor Luu, Maik, Pautz, Sabine, Kohl, Vanessa, Singh, Rajeev, Romero, Rossana, Lucas, Sébastien, Hofmann, Jörg, Raifer, Hartmann, Vachharajani, Niyati, Carrascosa, Lucia Campos, Lamp, Boris, Nist, Andrea, Stiewe, Thorsten, Shaul, Yoav, Adhikary, Till, Zaiss, Mario M., Lauth, Matthias, Steinhoff, Ulrich, Visekruna, Alexander
Vydáno v Nat Commun (2019)

Microbial short-chain fatty acids modulate CD8(+) T cell responses and improve adoptive immunotherapy for cancer

Autor Luu, Maik, Riester, Zeno, Baldrich, Adrian, Reichardt, Nicole, Yuille, Samantha, Busetti, Alessandro, Klein, Matthias, Wempe, Anne, Leister, Hanna, Raifer, Hartmann, Picard, Felix, Muhammad, Khalid, Ohl, Kim, Romero, Rossana, Fischer, Florence, Bauer, Christian A., Huber, Magdalena, Gress, Thomas M., Lauth, Matthias, Danhof, Sophia, Bopp, Tobias, Nerreter, Thomas, Mulder, Imke E., Steinhoff, Ulrich, Hudecek, Michael, Visekruna, Alexander
Vydáno v Nat Commun (2021)