Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control

Por Singh, Rajeev, Lauth, Matthias
Publicado no J Dev Biol (2017)

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

Por Singh, Rajeev, Dhanyamraju, Pavan Kumar, Lauth, Matthias
Publicado no Oncotarget (2016)

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

Por Lauth, Matthias, Spreafico, Fabio, Dethleffsen, Kathrin, Meyer, Michael
Publicado em 2002

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

Por Lauth, Matthias, Bergström, Åsa, Shimokawa, Takashi, Toftgård, Rune
Publicado em 2007

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1

Por Palaniswamy, Ramesh, Teglund, Stephan, Lauth, Matthias, Zaphiropoulos, Peter G, Shimokawa, Takashi
Publicado em 2010

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

Por Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Publicado em 2016

Novel Human Glioma-associated Oncogene 1 (GLI1) Splice Variants Reveal Distinct Mechanisms in the Terminal Transduction of the Hedgehog Signal

Por Shimokawa, Takashi, Tostar, Ulrica, Lauth, Matthias, Palaniswamy, Ramesh, Kasper, Maria, Toftgård, Rune, Zaphiropoulos, Peter G.
Publicado em 2008

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity

Por Barski, Jaroslaw J., Denker, Brad M., Guan, Jiazhen, Lauth, Matthias, Spreafico, Fabio, Fertala, Andrzej, Meyer, Michael
Publicado em 2013

Inhibition of GLI1 gene activation by Patched1

Por Rahnama, Fahimeh, Shimokawa, Takashi, Lauth, Matthias, Finta, Csaba, Kogerman, Priit, Teglund, Stephan, Toftgård, Rune, Zaphiropoulos, Peter G.
Publicado em 2006

Chronic Pancreatitis and Systemic Inflammatory Response Syndrome Prevent Impact of Chemotherapy with Gemcitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer()()

Por Knoop, Richard F., Sparn, Moritz, Waldmann, Jens, Plassmeier, Lars, Bartsch, Detlef K., Lauth, Matthias, Hudemann, Christoph, Fendrich, Volker
Publicado em 2014

Ectopic Overexpression of Sonic Hedgehog (Shh) Induces Stromal Expansion and Metaplasia in the Adult Murine Pancreas

Por Fendrich, Volker, Oh, Edwin, Bang, Seungmin, Karikari, Collins, Ottenhof, Niki, Bisht, Savita, Lauth, Matthias, Brossart, Peter, Katsanis, Nicholas, Maitra, Anirban, Feldmann, Georg
Publicado em 2011

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

Por Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Publicado no Nat Commun (2015)

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

Por Schneider, Philipp, Bayo-Fina, Juan Miguel, Singh, Rajeev, Dhanyamraju, Pavan Kumar, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Publicado no Nat Commun (2015)

The Immune Microenvironment in Pancreatic Cancer

Por Huber, Magdalena, Brehm, Corinna U., Gress, Thomas M., Buchholz, Malte, Alashkar Alhamwe, Bilal, Pogge von Strandmann, Elke, Slater, Emily P., Bartsch, Jörg W., Bauer, Christian, Lauth, Matthias
Publicado no Int J Mol Sci (2020)

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

Por Joost, Simon, Almada, Luciana L., Rohnalter, Verena, Holz, Philipp S., Vrabel, Anne M., Fernandez-Barrena, Maite G., McWilliams, Robert R., Krause, Michael, Fernandez-Zapico, Martin E., Lauth, Matthias
Publicado em 2011

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Por Luu, Maik, Pautz, Sabine, Kohl, Vanessa, Singh, Rajeev, Romero, Rossana, Lucas, Sébastien, Hofmann, Jörg, Raifer, Hartmann, Vachharajani, Niyati, Carrascosa, Lucia Campos, Lamp, Boris, Nist, Andrea, Stiewe, Thorsten, Shaul, Yoav, Adhikary, Till, Zaiss, Mario M., Lauth, Matthias, Steinhoff, Ulrich, Visekruna, Alexander
Publicado no Nat Commun (2019)