Llwytho...

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

Aberrant activation of the transcription factor GLI1, a central effector of the Hedgehog (HH) pathway, is associated with several malignancies, including pancreatic ductal adenocarcinoma (PDAC), one of most deadly human cancers. GLI1 has been described as an oncogene in PDAC, making it a promising t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: F1000Research 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207242/
https://ncbi.nlm.nih.gov/pubmed/25352983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.5324.2
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!