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Canonical Wnt signaling Is required for pancreatic carcinogenesis

Wnt ligand expression and activation of the Wnt/β-catenin pathway have been associated with pancreatic ductal adenocarcinoma, but whether Wnt activity is required for the development of pancreatic cancer has remained unclear. Here we report the results of three different approaches to inhibit the Wn...

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Detalhes bibliográficos
Main Authors: Zhang, Yaqing, Morris, John P., Yan, Wei, Schofield, Heather K., Gurney, Austin, Simeone, Diane M., Millar, Sarah E., Hoey, Timothy, Hebrok, Matthias, di Magliano, Marina Pasca
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763696/
https://ncbi.nlm.nih.gov/pubmed/23761328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-4384
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