Common Activation of Canonical Wnt Signaling in Pancreatic Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is an extremely aggressive malignancy, which carries a dismal prognosis. Activating mutations of the Kras gene are common to the vast majority of human PDA. In addition, recent studies have demonstrated that embryonic signaling pathway such as Hedgehog and Notc...

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書誌詳細
主要な著者: Pasca di Magliano, Marina, Biankin, Andrew V., Heiser, Patrick W., Cano, David A., Gutierrez, Pedro J. A., Deramaudt, Therese, Segara, Davendra, Dawson, Amanda C., Kench, James G., Henshall, Susan M., Sutherland, Robert L., Dlugosz, Andrzej, Rustgi, Anil K., Hebrok, Matthias
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2007
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048934/
https://ncbi.nlm.nih.gov/pubmed/17982507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001155
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