Common Activation of Canonical Wnt Signaling in Pancreatic Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDA) is an extremely aggressive malignancy, which carries a dismal prognosis. Activating mutations of the Kras gene are common to the vast majority of human PDA. In addition, recent studies have demonstrated that embryonic signaling pathway such as Hedgehog and Notc...

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Detalhes bibliográficos
Main Authors: Pasca di Magliano, Marina, Biankin, Andrew V., Heiser, Patrick W., Cano, David A., Gutierrez, Pedro J. A., Deramaudt, Therese, Segara, Davendra, Dawson, Amanda C., Kench, James G., Henshall, Susan M., Sutherland, Robert L., Dlugosz, Andrzej, Rustgi, Anil K., Hebrok, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2048934/
https://ncbi.nlm.nih.gov/pubmed/17982507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001155
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