The Transcription Factor GLI1 Modulates the Inflammatory Response during Pancreatic Tissue Remodeling

Pancreatic cancer, one of the deadliest human malignancies, is almost uniformly associated with a mutant, constitutively active form of the oncogene Kras. Studies in genetically engineered mouse models have defined a requirement for oncogenic KRAS in both the formation of pancreatic intraepithelial...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mathew, Esha, Collins, Meredith A., Fernandez-Barrena, Maite G., Holtz, Alexander M., Yan, Wei, Hogan, James O., Tata, Zachary, Allen, Benjamin L., Fernandez-Zapico, Martin E., Pasca di Magliano, Marina
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183809/
https://ncbi.nlm.nih.gov/pubmed/25104358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556563
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