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Inactivation of the Transcription Factor GLI1 Accelerates Pancreatic Cancer Progression

The role of GLI1 in pancreatic tumor initiation promoting the progression of preneoplastic lesions into tumors is well established. However, its function at later stages of pancreatic carcinogenesis remains poorly understood. To address this issue, we crossed the gli1 knock-out (GKO) animal with cre...

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Detalhes bibliográficos
Main Authors: Mills, Lisa D., Zhang, Lizhi, Marler, Ronald, Svingen, Phyllis, Fernandez-Barrena, Maite G., Dave, Maneesh, Bamlet, William, McWilliams, Robert R., Petersen, Gloria M., Faubion, William, Fernandez-Zapico, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047418/
https://ncbi.nlm.nih.gov/pubmed/24737325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539031
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