DOSAGE-DEPENDENT REGULATION OF PANCREATIC CANCER GROWTH AND ANGIOGENESIS BY HEDGEHOG SIGNALING

Pancreatic cancer, a hypovascular and highly desmoplastic cancer, is characterized by tumor expression of Hedgehog (HH) ligands which signal to fibroblasts in the surrounding stroma that in turn promote tumor survival and growth. However, the mechanisms and consequences of stromal HH pathway activat...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Mathew, Esha, Zhang, Yaqing, Holtz, Alexander M., Kane, Kevin T., Song, Jane Y., Allen, Benjamin L., Pasca di Magliano, Marina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362534/
https://ncbi.nlm.nih.gov/pubmed/25310976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.010
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