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Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme
Although general mechanisms of RNA folding and catalysis have been elucidated, little is known about how ribozymes achieve structural stability at high temperature. A previous in vitro evolution experiment identified a small number of mutations that significantly increase the thermostability of the...
में बचाया:
| मुख्य लेखकों: | , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Copyright 2006 by RNA Society
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383578/ https://ncbi.nlm.nih.gov/pubmed/16431981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2198206 |
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