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Suppression of mutations in the core of the Tetrahymena ribozyme by spermidine, ethanol and by substrate stabilization.

We have previously described a collection of mutations in conserved residues of the core of the Tetrahymena self-splicing intron. Most of these single base substitutions have less than 10% of the activity of their parental intron derivative [Couture, S., et al., (1990) J. Mol. Biol., 215, 345-358]....

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Detalles Bibliográficos
Autores principales: Hanna, M, Szostak, J W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC332078/
https://ncbi.nlm.nih.gov/pubmed/7816622
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