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The thermodynamic origin of the stability of a thermophilic ribozyme

Understanding the mechanism of thermodynamic stability of an RNA structure has significant implications for the function and design of RNA. We investigated the equilibrium folding of a thermophilic ribozyme and its mesophilic homologue by using hydroxyl radical protection, small-angle x-ray scatteri...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Fang, X.-W., Golden, B. L., Littrell, K., Shelton, V., Thiyagarajan, P., Pan, T., Sosnick, T. R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2001
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31839/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071050698
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