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The thermodynamic origin of the stability of a thermophilic ribozyme

Understanding the mechanism of thermodynamic stability of an RNA structure has significant implications for the function and design of RNA. We investigated the equilibrium folding of a thermophilic ribozyme and its mesophilic homologue by using hydroxyl radical protection, small-angle x-ray scatteri...

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Hlavní autoři: Fang, X.-W., Golden, B. L., Littrell, K., Shelton, V., Thiyagarajan, P., Pan, T., Sosnick, T. R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC31839/
https://ncbi.nlm.nih.gov/pubmed/11296284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071050698
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