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Nonequilibrium mechanism of transcription termination from observations of single RNA polymerase molecules

Cessation of transcription at specific terminator DNA sequences is used by viruses, bacteria, and eukaryotes to regulate the expression of downstream genes, but the mechanisms of transcription termination are poorly characterized. To elucidate the kinetic mechanism of termination at the intrinsic te...

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Detalhes bibliográficos
Main Authors: Yin, Hong, Artsimovitch, Irina, Landick, Robert, Gelles, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23911/
https://ncbi.nlm.nih.gov/pubmed/10557284
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