Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene

Several low-fidelity DNA polymerases have recently been discovered that are able to bypass DNA lesions during DNA synthesis in vitro. The efficiency and accuracy of lesion bypass is, however, both polymerase and lesion specific. For example, in vitro studies revealed that human DNA polymerase κ (Pol...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Ogi, Tomoo, Shinkai, Yoichi, Tanaka, Kiyoji, Ohmori, Haruo
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 2002
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12432099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222377899
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