Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene
Several low-fidelity DNA polymerases have recently been discovered that are able to bypass DNA lesions during DNA synthesis in vitro. The efficiency and accuracy of lesion bypass is, however, both polymerase and lesion specific. For example, in vitro studies revealed that human DNA polymerase κ (Pol...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12432099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222377899 |
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