Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene

Several low-fidelity DNA polymerases have recently been discovered that are able to bypass DNA lesions during DNA synthesis in vitro. The efficiency and accuracy of lesion bypass is, however, both polymerase and lesion specific. For example, in vitro studies revealed that human DNA polymerase κ (Pol...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ogi, Tomoo, Shinkai, Yoichi, Tanaka, Kiyoji, Ohmori, Haruo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12432099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222377899
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