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Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene

Several low-fidelity DNA polymerases have recently been discovered that are able to bypass DNA lesions during DNA synthesis in vitro. The efficiency and accuracy of lesion bypass is, however, both polymerase and lesion specific. For example, in vitro studies revealed that human DNA polymerase κ (Pol...

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Bibliografski detalji
Glavni autori: Ogi, Tomoo, Shinkai, Yoichi, Tanaka, Kiyoji, Ohmori, Haruo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC137754/
https://ncbi.nlm.nih.gov/pubmed/12432099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222377899
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