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Increased mitochondrial mass in mitochondrial myopathy mice
We have generated an animal model for mitochondrial myopathy by disrupting the gene for mitochondrial transcription factor A (Tfam) in skeletal muscle of the mouse. The knockout animals developed a myopathy with ragged-red muscle fibers, accumulation of abnormally appearing mitochondria, and progres...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137544/ https://ncbi.nlm.nih.gov/pubmed/12417746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232591499 |
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