Increased mitochondrial mass in mitochondrial myopathy mice

We have generated an animal model for mitochondrial myopathy by disrupting the gene for mitochondrial transcription factor A (Tfam) in skeletal muscle of the mouse. The knockout animals developed a myopathy with ragged-red muscle fibers, accumulation of abnormally appearing mitochondria, and progres...

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Detaylı Bibliyografya
Asıl Yazarlar: Wredenberg, Anna, Wibom, Rolf, Wilhelmsson, Hans, Graff, Caroline, Wiener, Heidi H., Burden, Steven J., Oldfors, Anders, Westerblad, Håkan, Larsson, Nils-Göran
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC137544/
https://ncbi.nlm.nih.gov/pubmed/12417746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232591499
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