Loading...
A role for the exosome in the in vivo degradation of unstable mRNAs
In mammals, the mRNAs encoding many proteins involved in inflammation bear destabilizing AU-rich elements (AREs) in the 3′-untranslated region. The exosome, a complex of 3′ → 5′ exonucleases, is rate limiting in the destruction of such mRNAs in a mammalian in vitro system, but a role in vivo has not...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Copyright 2003 by RNA Society
2003
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370503/ https://ncbi.nlm.nih.gov/pubmed/14624005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5940703 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|