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Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs

Two general pathways of mRNA decay have been characterized in yeast. In one pathway, the mRNA is degraded by the cytoplasmic form of the exosome. The exosome has both 3′ to 5′ exoribonuclease and endoribonuclease activity, and the available evidence suggests that the exonuclease activity is required...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Schaeffer, Daneen, van Hoof, Ambro
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038778/
https://ncbi.nlm.nih.gov/pubmed/21262801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013180108
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