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Degradation of mRNAs that lack a stop codon: A decade of nonstop progress

Nonstop decay is the mechanism of identifying and disposing aberrant transcripts that lack in-frame stop codons. It is hypothesized that these transcripts are identified during translation when the ribosome arrives at the 3′ end of the mRNA and stalls. Presumably the ribosome stalling recruits addit...

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Sonraí Bibleagrafaíochta
Main Authors: Klauer, A. Alejandra, van Hoof, Ambro
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638749/
https://ncbi.nlm.nih.gov/pubmed/22740367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1124
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