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Degradation of mRNAs that lack a stop codon: A decade of nonstop progress
Nonstop decay is the mechanism of identifying and disposing aberrant transcripts that lack in-frame stop codons. It is hypothesized that these transcripts are identified during translation when the ribosome arrives at the 3′ end of the mRNA and stalls. Presumably the ribosome stalling recruits addit...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638749/ https://ncbi.nlm.nih.gov/pubmed/22740367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1124 |
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