Codon bias confers stability to human mRNAs

Codon bias has been implicated as one of the major factors contributing to mRNA stability in several model organisms. However, the molecular mechanisms of codon bias on mRNA stability remain unclear in humans. Here, we show that human cells possess a mechanism to modulate RNA stability through a uni...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Hia, Fabian, Yang, Sheng Fan, Shichino, Yuichi, Yoshinaga, Masanori, Murakawa, Yasuhiro, Vandenbon, Alexis, Fukao, Akira, Fujiwara, Toshinobu, Landthaler, Markus, Natsume, Tohru, Adachi, Shungo, Iwasaki, Shintaro, Takeuchi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831995/
https://ncbi.nlm.nih.gov/pubmed/31482640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948220
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