Codon bias confers stability to human mRNAs

Codon bias has been implicated as one of the major factors contributing to mRNA stability in several model organisms. However, the molecular mechanisms of codon bias on mRNA stability remain unclear in humans. Here, we show that human cells possess a mechanism to modulate RNA stability through a uni...

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Pubblicato in:EMBO Rep
Autori principali: Hia, Fabian, Yang, Sheng Fan, Shichino, Yuichi, Yoshinaga, Masanori, Murakawa, Yasuhiro, Vandenbon, Alexis, Fukao, Akira, Fujiwara, Toshinobu, Landthaler, Markus, Natsume, Tohru, Adachi, Shungo, Iwasaki, Shintaro, Takeuchi, Osamu
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831995/
https://ncbi.nlm.nih.gov/pubmed/31482640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948220
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