Codon bias confers stability to human mRNAs

Codon bias has been implicated as one of the major factors contributing to mRNA stability in several model organisms. However, the molecular mechanisms of codon bias on mRNA stability remain unclear in humans. Here, we show that human cells possess a mechanism to modulate RNA stability through a uni...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Hia, Fabian, Yang, Sheng Fan, Shichino, Yuichi, Yoshinaga, Masanori, Murakawa, Yasuhiro, Vandenbon, Alexis, Fukao, Akira, Fujiwara, Toshinobu, Landthaler, Markus, Natsume, Tohru, Adachi, Shungo, Iwasaki, Shintaro, Takeuchi, Osamu
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831995/
https://ncbi.nlm.nih.gov/pubmed/31482640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948220
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