Codon bias confers stability to human mRNAs

Codon bias has been implicated as one of the major factors contributing to mRNA stability in several model organisms. However, the molecular mechanisms of codon bias on mRNA stability remain unclear in humans. Here, we show that human cells possess a mechanism to modulate RNA stability through a uni...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Hia, Fabian, Yang, Sheng Fan, Shichino, Yuichi, Yoshinaga, Masanori, Murakawa, Yasuhiro, Vandenbon, Alexis, Fukao, Akira, Fujiwara, Toshinobu, Landthaler, Markus, Natsume, Tohru, Adachi, Shungo, Iwasaki, Shintaro, Takeuchi, Osamu
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831995/
https://ncbi.nlm.nih.gov/pubmed/31482640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948220
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