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Codon bias confers stability to human mRNAs

Codon bias has been implicated as one of the major factors contributing to mRNA stability in several model organisms. However, the molecular mechanisms of codon bias on mRNA stability remain unclear in humans. Here, we show that human cells possess a mechanism to modulate RNA stability through a uni...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Hia, Fabian, Yang, Sheng Fan, Shichino, Yuichi, Yoshinaga, Masanori, Murakawa, Yasuhiro, Vandenbon, Alexis, Fukao, Akira, Fujiwara, Toshinobu, Landthaler, Markus, Natsume, Tohru, Adachi, Shungo, Iwasaki, Shintaro, Takeuchi, Osamu
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831995/
https://ncbi.nlm.nih.gov/pubmed/31482640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948220
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