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Degradation of mRNAs that lack a stop codon: A decade of nonstop progress

Nonstop decay is the mechanism of identifying and disposing aberrant transcripts that lack in-frame stop codons. It is hypothesized that these transcripts are identified during translation when the ribosome arrives at the 3′ end of the mRNA and stalls. Presumably the ribosome stalling recruits addit...

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Bibliografiska uppgifter
Huvudupphovsmän: Klauer, A. Alejandra, van Hoof, Ambro
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638749/
https://ncbi.nlm.nih.gov/pubmed/22740367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1124
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