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Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences
The turnover of messenger RNAs (mRNAs) is a key regulatory step of gene expression in eukaryotic cells. Due to the complexity of the mammalian degradation machinery, the contribution of decay factors to the directionality of mRNA decay is poorly understood. Here we characterize a molecular tool to i...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150221/ https://ncbi.nlm.nih.gov/pubmed/27917860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13691 |
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