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Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences
The turnover of messenger RNAs (mRNAs) is a key regulatory step of gene expression in eukaryotic cells. Due to the complexity of the mammalian degradation machinery, the contribution of decay factors to the directionality of mRNA decay is poorly understood. Here we characterize a molecular tool to i...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150221/ https://ncbi.nlm.nih.gov/pubmed/27917860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13691 |
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