pH-dependent conformational flexibility within the ribosomal peptidyl transferase center.

A universally conserved adenosine, A2451, within the ribosomal peptidyl transferase center has been proposed to act as a general acid-base catalyst during peptide bond formation. Evidence in support of this proposal came from pH-dependent dimethylsulfate (DMS) modification within Escherichia coli ri...

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Bibliografiske detaljer
Main Authors: Muth, G W, Chen, L, Kosek, A B, Strobel, S A
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370184/
https://ncbi.nlm.nih.gov/pubmed/11680845
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