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Modulating the activity of the peptidyl transferase center of the ribosome
The peptidyl transferase (PT) center of the ribosome catalyzes two nucleophilic reactions, peptide bond formation between aminoacylated tRNA substrates and, together with release factor, peptide release. Structure and function of the PT center are modulated by binding of aminoacyl-tRNA or release fa...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327356/ https://ncbi.nlm.nih.gov/pubmed/18369182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.980308 |
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