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A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition
The ribosome is a dynamic particle that undergoes many structural changes during translation. We show through chemical probing with dimethyl sulfate (DMS) that conformational changes occur at several nucleotides in the peptidyl transferase center upon alterations in pH, temperature, and monovalent i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC56921/ https://ncbi.nlm.nih.gov/pubmed/11517305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171319598 |
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