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Mobilization of RAG-Generated Signal Ends by Transposition and Insertion In Vivo
In addition to their essential roles in V(D)J recombination, the RAG proteins have been found to catalyze transposition in vitro, but it has been difficult to demonstrate transposition by the RAG proteins in vivo in vertebrate cells. As genomic instability and chromosomal translocations are common o...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367191/ https://ncbi.nlm.nih.gov/pubmed/16449665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.4.1558-1568.2006 |
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