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Structures of a RAG-like transposase during cut-and-paste transposition

Transposons have played a pivotal role in genome evolution(1) and are believed to be the evolutionary progenitors of the RAG1-RAG2 recombinase(2), an essential component of the adaptive immune system in jawed vertebrates(3). Here we report one crystal and five cryo-electron microscopy structures of...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Liu, Chang, Yang, Yang, Schatz, David G.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872938/
https://ncbi.nlm.nih.gov/pubmed/31723264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1753-7
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