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Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination
In addition to creating the DNA double strand breaks that initiate V(D)J recombination, the RAG proteins are thought to play a critical role in the joining phase of the reaction. One such role, suggested by in vitro studies, might be to ensure the structural integrity of postcleavage complexes, but...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2002
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC186421/ https://ncbi.nlm.nih.gov/pubmed/12154124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.984502 |
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