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Mobilization of RAG-Generated Signal Ends by Transposition and Insertion In Vivo

In addition to their essential roles in V(D)J recombination, the RAG proteins have been found to catalyze transposition in vitro, but it has been difficult to demonstrate transposition by the RAG proteins in vivo in vertebrate cells. As genomic instability and chromosomal translocations are common o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chatterji, Monalisa, Tsai, Chia-Lun, Schatz, David G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367191/
https://ncbi.nlm.nih.gov/pubmed/16449665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.4.1558-1568.2006
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