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Equilibrium and Kinetic Folding Pathways of a TIM Barrel with a Funneled Energy Landscape
The role of native contact topology in the folding of a TIM barrel model based on the α-subunit of tryptophan synthase (αTS) from Salmonella typhimurium (Protein Data Bank structure 1BKS) was studied using both equilibrium and kinetic simulations. Equilibrium simulations of αTS reveal the population...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Biophysical Society
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366549/ https://ncbi.nlm.nih.gov/pubmed/15833999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.059147 |
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